Article brought to you by: Catholic Online (www.catholic.org)

New malaria vaccine proved to be 100 percent effective

By Catholic Online (NEWS CONSORTIUM)
August 12th, 2013
Catholic Online (www.catholic.org)

A cure for malaria would be an enormous boon for all mankind. The mosquito-born virus continues to decimate large swaths of Asia and Africa, a new vaccine has proved to be 100 percent effective against the ravages of the disease, "...This is a pivotal success," Stefan Kappe, a malaria researcher at the Seattle Biomedical Research Institute in Washington says.

LOS ANGELES, CA (Catholic Online) - A company in Rockville, Maryland, Sanaria, has developed a vaccine that has become the first in providing 100% protection against the deadly disease. Called PfSPZ because its makeup is comprised of sporozoites (SPZ,) a stage of malarial parasite Plasmodium falciparum (Pf,) uses a weakened form of the malaria organism to instigate a response from the immune system.

Six subjects were given five doses intravenously in the safety trial's first phase. All were found to be protected from test bites of infectious mosquitos. Five of six unvaccinated control subjects developed malaria.

"The trial results constitute the most important advance in malaria vaccine development since the first demonstration of protection with radiation attenuated sporozoite immunization by mosquito bite in the 70s. This is a pivotal success," Kappe said.

The trial will now need to be addressed to a wider array of subjects to see if the vaccine will work on the varied strains of the disease and if it continues to provide the same protection for both men and women of different ages.

Treatment of malaria depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired. The latter 2 characteristics help determine the probability that the organism is resistant to certain antimalarial drugs. Additional factors such as age, weight, and pregnancy status may limit the available options for malaria treatment.

Article brought to you by: Catholic Online (www.catholic.org)