Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

2/17/2013 (1 year ago)

Catholic Online (www.catholic.org)

Rare, one-of-a-kind disease may be treated with DNA mapping

Thirty-eight-year-old Briton Mandy Sellars has a rare disease that has made her legs grow freakishly huge, weighing 238 pounds by themselves. Now doctors say they have developed a promising treatment for her after mapping her DNA.

Incredibly difficult for her to move around, Mandy Sellars is housebound during the week. She travels in a specially reinforced wheelchair.

Incredibly difficult for her to move around, Mandy Sellars is housebound during the week. She travels in a specially reinforced wheelchair.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

2/17/2013 (1 year ago)

Published in Health

Keywords: Rare disease, gigantism, DNA mapping, United Kingdom


LOS ANGELES, CA (Catholic Online) - Sellars has a condition that has caused her legs to grow out of control her entire life. She had her massive left leg amputated after it became infected with septicaemia. Incredibly, the stump started growing again and within three years measured a meter in circumference and weighed 42 pounds.

Her condition is unnamed, following genetic testing. Her case is the first case of its kind in the world.

Incredibly difficult for her to move around, she is housebound during the week. She travels in a specially reinforced wheelchair.

Doctors had hoped to fit her with a prosthetic leg but as her stump kept growing, new legs had to be made and to date she is still unable to walk.

"I find it incredibly frustrating," Sellars, from Huncoat in Lancashire says. "I have such a zest for life and I really want to get out there and live it."

Scientists at Cambridge University took an interest in Sellars' case, and over the past year, Dr. Robert Semple has mapped her DNA from blood and tissue samples.

Sellars previously thought she had a rare form of Proteus Syndrome, the condition that affected the Elephant Man. However, the analysis revealed she had a unique disorder.

"I'm the first person in the world with it and it hasn't even got a name yet," she told a TV chat show. "I keep suggesting Dr Semple call it Sellars Syndrome!"

Dr. Semple's team has come up with a medication aimed at replacing her unique mutated gene with a therapeutic gene. "I started taking it in September and the aim was to stop my limbs growing further. Actually they have started to shrink a little," Sellars said.

"I just kind of accepted my condition would get worse and keep growing but I am more optimistic following the discovery."

A size 12 on her top half, Sellars has had to deal with her one in seven billion conditions her entire life.

"There was clearly something dramatically different about me when I was born as my legs were so much bigger than my body. Doctors didn't know what it was and whisked me away - they didn't let my mother see me for two weeks. They didn't think I would survive."

Despite of all of her hardships, Sellars remains optimistic. "I really miss travelling and I hope one day to walk again," she said. "I'm stubborn enough to make it happen!"

---


Pope Francis: end world hunger through 'Prayer and Action'


© 2014 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for October 2014
Peace:
That the Lord may grant peace to those parts of the world most battered by war and violence.
World Mission Day: That World Mission Day may rekindle in every believer zeal for carrying the Gospel into all the world.



Comments


More Health

What's the biggest danger in your home? It will shock and disgust you Watch

Image of Kitchen towels in your home may be the biggest danger to the health of you and your family.

By Catholic Online (NEWS CONSORTIUM)

The biggest danger in your house aren't stairs, bugs or chemicals, but actually may be hand towels kept in the kitchen. LOS ANGELES, CA (Catholic Online) - Kitchen towels may spread food poisoning, bacteria or other dangerous microorganisms around your home without any ... continue reading


NOT long enough: Ebola could lay dormant in the body for longer than 21 days, expert claims Watch

Image of Biology Professor Charles Hass, who has vast experience of analyzing the risk of transmitting biological pathogens, said

By Catholic Online (NEWS CONSORTIUM)

A new study warns that the recommended 21-day quarantine period for the Ebola virus is not long enough to contain the spread of the disease. While the World Health Organization advises the incubation period for the virus is between two and 21 days, scientists ... continue reading


Nurse says Texas Presbyterian Hospital was chaotic and filthy during Ebola outbreak Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

Texas Presbyterian Hospital in Dallas, Texas, reacted very poorly when it discovered that they had been treating a Liberian man with Ebola. According to a nurse who has since come forward, safety regulations were blithely ignored, contaminated linens and waste ... continue reading


Why aren't we doing this? Colombia bans entry to those from Ebola affected countries Watch

Image of A Liberian man is having his temperature taken by a no-contact thermometer.

By Catholic Online (NEWS CONSORTIUM)

Two countries have started barring entry to people coming from the nations in West Africa that have been hardest hit by the current Ebola outbreak. LOS ANGELES, CA (Catholic Online) - Kenny Anthony, the prime minister of St. Lucia-a small island nation in the ... continue reading


Second Dallas health worker contracts Ebola virus Watch

Image of Workers scrub down Amber Vinson's apartment in Dallas, Texas.

By Catholic Online (NEWS CONSORTIUM)

A second Dallas health care worker has since contracted the Ebola virus - and authorities are now frantically trying to contact the more than 100 plus passengers with whom she shared a flight. Authorities says that the employee, Amber Vinson reportedly showed ... continue reading


World has until Christmas to control Ebola; all bets off afterwards Watch

Image of The World Health Organization, or WHO earlier said there could be 10,000 new cases of Ebola per week within two months.

By Catholic Online (NEWS CONSORTIUM)

The United Nations says the Ebola outbreak must be controlled within 60 days. Otherwise, the world faces an "unprecedented" situation for which there is no plan. Ebola, according to the U.N. "is running faster than us and it is winning the race." LOS ANGELES, ... continue reading


The horrifying truth of Ebola: WHO suggests 10,000 could become infected per week Watch

Image of An aid worker carries a child infected with Ebola in Liberia, one of the West African nations hardest hit by the outbreak.

By Catholic Online (NEWS CONSORTIUM)

The World Health Organization (WHO) has issued a dire warning to the world. On October 14 they announced that the death rate of the current Ebola outbreak in West Africa is now 70%, much higher than usual. Even more horrifying, the WHO has stated that West Africa ... continue reading


Ebola is 'the most severe, acute health emergency seen in modern times' -- WHO Watch

Image of Ninety percent of economic costs of any outbreak

By Catholic Online (NEWS CONSORTIUM)

Deaths from the currently Ebola epidemic has sailed past the 4,000 mark this week, with the majority of deaths confined to West Africa: Liberia, Sierra Leone and Guinea are the nations most impacted by the disease. But as the first death in the United States from Ebola ... continue reading


Stem cell breakthrough could save diabetics from daily injections Watch

Image of Patients could receive a single transplant with the newly generated cells, which would then read out the amount of sugar in the blood and squirt out just the right amount of the hormone insulin.

By Catholic Online (NEWS CONSORTIUM)

Scientists have announced a stem cell breakthrough that could one day free millions of diabetics from a lifetime of insulin injections. Stem cell researcher Douglas Melton has conceived of a method of growing billions of precious insulin-secreting cells en ... continue reading


Safety protocols called into question after first case of Ebola contracted on U.S. soil Watch

Image of More than 4,000 people have died of Ebola since the start of the year usually in Guinea, Sierra Leone and Liberia. The epidemic appears to be outpacing efforts to fight it.

By Catholic Online (NEWS CONSORTIUM)

While Thomas Duncan from Liberia may have been America's "patient zero" in regards to Ebola, the nurse who treated him that has since fallen ill from the disease represents the first instance of Ebola being contracted on U.S. soil. Health officials, who believe ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, Ephesians 2:12-22
12 do not forget, I say, that you were at that time ... Read More

Psalm, Psalms 85:9-10, 11-12, 13-14
9 His saving help is near for those who fear him, his ... Read More

Gospel, Luke 12:35-38
35 'See that you have your belts done up and your ... Read More

Saint of the Day

Saint of the Day for October 21st, 2014 Image

St. Hilarion
October 21: Abbot and disciple of St. Anthony the Great, companion of St. ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter