Skip to content
Catholic Online Logo

By Catholic Online (NEWS CONSORTIUM)

2/10/2013 (1 year ago)

Catholic Online (www.catholic.org)

Unlike radiotherapy or chemotherapy, new method is not toxic to body

A new method in battling cancer has been developed by scientists. Unlike such toxic and invasive techniques such as radiotherapy or chemotherapy, the new method makes the body itself destroy cancerous cells.

'We didn't actually anticipate that this molecule would be able to treat brain tumors - that was a pleasant surprise,' lead researcher Wafik El-Deiry, an oncologist at Pennsylvania State University says.

"We didn't actually anticipate that this molecule would be able to treat brain tumors - that was a pleasant surprise," lead researcher Wafik El-Deiry, an oncologist at Pennsylvania State University says.

Highlights

By Catholic Online (NEWS CONSORTIUM)

Catholic Online (www.catholic.org)

2/10/2013 (1 year ago)

Published in Health

Keywords: Cancer, Pennsylvania State University, TIC10, Wafik El-Deiry


LOS ANGELES, CA (Catholic Online) - Pennsylvania State University researchers have identified a molecule -- TIC10 -- which activates a protein that helps fight the disease. The protein, called TRAIL, which stands for tumor-necrosis-factor-related apoptosis-inducing ligand,  suppresses tumor development during immune surveillance, which is the immune system's process of patrolling the body for cancer cells.

Typically, this process is lost during cancer progression, which leads to uncontrolled growth and spread of tumors. The chief benefit of using TRAIL is that it is already part of the immune system, unlike the medication that is introduced into the body, leaving behind toxic after effects. 

The microscopic size of TIC10 also makes it more effective than past discoveries as it can cross the blood-brain barrier, which separates the main circulatory system from the brain.

This barrier can prevent cancer treatments from entering the brain, thereby hindering the action of drugs for brain tumors. "We didn't actually anticipate that this molecule would be able to treat brain tumors - that was a pleasant surprise," lead researcher Wafik El-Deiry, an oncologist at Pennsylvania State University says.

An added bonus is that TIC10 does not just activate the TRAIL gene in cancerous cells, but also in healthy ones. Known as the "bystander effect," this is where cells near cancerous cells are also killed.

Nearby healthy cells are also given a boost to increase the number of cancer-killing TRAIL receptors on their cell surface.

El-Deiry is confident that a similar approach would work in humans. "I was surprised and impressed that we were able to do this," noting that previous experiments have been conducted on lab animals.

"Using a small molecule to significantly boost and overcome limitations of the TRAIL pathway appears to be a promising way to address difficult to treat cancers using a safe mechanism already used in those with a normal effective immune system.

"The TRAIL pathway is a powerful way to suppress tumors but current approaches have limitations that we have been trying to overcome to unleash an effective and selective cancer therapy,' El-Deiry says.

The success of TRAIL to trigger cancer cell death has led to ongoing clinical trials with artificially created versions, and early trials have shown that giving the protein in drug form is safe.

---


Pope Francis: end world hunger through 'Prayer and Action'


2014 - Distributed by THE NEWS CONSORTIUM

Pope Francis Prayer Intentions for September 2014
Mentally disabled:
That the mentally disabled may receive the love and help they need for a dignified life.
Service to the poor: That Christians, inspired by the Word of God, may serve the poor and suffering.



Comments


More Health

This disease may foretell diabetes, heart attacks, or cancer and you may just have it! Watch

Image of Those with pre-diabetes can lower their chance of contracting diabetes with a healthy diet, exercise and weight loss.

By Catholic Online (NEWS CONSORTIUM)

Federal health statistics show that nearly half of all adults in the U.S. have either pre-diabetes or diabetes, severely raising their risk for heart attacks, blindness, amputations and cancer. LOS ANGELES, CA (Catholic Online) - These statistics show that 12.3% of ... continue reading


Are officials keeping facts about Ebola from the easily frightened public? Watch

Image of Some think the United Nations needs to address the Ebola crisis head on.

By Catholic Online (NEWS CONSORTIUM)

The current Ebola outbreak has the world terrified. While still largely confined to West Africa, there is very little the world can do to prevent an infected person from jumping on a plane and bringing it to another country. Are health officials deliberately ... continue reading


Anti-anxiety, sleeping pills now linked to onset of Alzheimer's disease Watch

Image of A special class of drugs used to reduce anxiety and induce sleep is now being blamed for increasing the risk of Alzheimer's twofold, according to a dismaying new report.

By Catholic Online (NEWS CONSORTIUM)

It now appears that the elderly have been taking a class of drugs to beat one condition, only to increase their risk for the dreaded memory-robbing diseases of Alzheimer's and dementia. A special class of drugs used to reduce anxiety and induce sleep is now ... continue reading


Amazing! Your computer might be able to tell if you have a heart condition Watch

Image of A pilot study has shown that a computer camera may be capable of telling when a person is having a heart condition, by picking up changes in skin tone.

By Catholic Online (NEWS CONSORTIUM)

Researchers may be able to accurately detect atrial fibrillation with just a regular laptop camera and some sophisticated software, a new pilot study reveals. LOS ANGELES, CA (Catholic Online) - The study reveals that this new system may be as accurate as a ... continue reading


Rare, unidentified illness striking nation's children Watch

Image of The rare new respiratory illness stalking the nation's children begins like an ordinary cold -- and then become much more serious.

By Catholic Online - (NEWS CONSORTIUM)

It's of high concern to the nation's parents: Thousands of kids in at least 10 U.S. have fallen ill to a mysterious respiratory illness. Doctors warn that this is likely to become a widespread, nationwide problem as the weather begins to cool. LOS ANGELES, CA ... continue reading


Every two minutes, an Indian commits suicide, new WHO study reveals Watch

Image of A new study from the World Health Organization has revealed that a third of all suicides in the world take place in India.

By Catholic Online (NEWS CONSORTIUM)

Every 40 seconds a person commits suicides, and a decade long study conduced by the World Health Organization (WHO) has revealed that every third suicide in the world takes place in India. LOS ANGELES, CA (Catholic Online) - The WHO believes that in 2012 alone, ... continue reading


New study shows that people with diabetes are more likely to suffer from tuberculosis Watch

Image of The rise of tuberculosis cases is especially hard hitting in Africa, where diabetes is also increasing.

By Catholic Online (NEWS CONSORTIUM)

The increasing number of Type 2 diabetes cases worldwide is going to make it more difficult to control and eliminate tuberculosis, experts have said after finding a connection between the two diseases. LOS ANGELES, CA (Catholic Online) - The reasons are still ... continue reading


Electric shocks to the brain can aid those who suffer from stroke, Alzheimer's, memory loss Watch

Image of Previously, TMS has been used in a limited way to temporarily change brain function to improve performance during a test. The new study shows that TMS can be used to improve memory for events at least 24 hours after the stimulation is given.

By Catholic Online (NEWS CONSORTIUM)

Applying electric shocks to the brain can improve memory, researchers have found. Furthermore, researchers say the discovery could develop exciting new approaches for treating strokes, early-stage Alzheimer's and aging on the brain. LOS ANGELES, CA (Catholic ... continue reading


Do you eat pomegranates? Well here's a few reasons why you should Watch

Image of Pomegranates contain the chemical punicalagin, a form of a chemical compound known as polyphenol, which may help to prevent the inflammation that destroys brain cells known as micrologia.

By Catholic Online (NEWS CONSORTIUM)

An ingredient in pomegranate may help stop the spread of Alzheimer's disease, scientists from the University of Huddersfield claim. LOS ANGELES, CA (Catholic Online) - The chemical punicalagin, a form of a chemical compound known as polyphenol, helps prevent the ... continue reading


NEW HOPE IN EBOLA CRISIS: U.S. doctor released from hospital - cured Watch

Image of

By Catholic Online (NEWS CONSORTIUM)

Contracting the deadly African virus while he worked to save their lives, Dr. Kent Brantly became one of the handful of people from the United States to contract Ebola. Receiving treatment back in the U.S., Brantly walked out of the hospital to the waiting arms ... continue reading


All Health News

Newsletters

Newsletter Sign Up icon

Stay up to date with the latest news, information, and special offers

Daily Readings

Reading 1, First Corinthians 12:12-14, 27-31
12 For as with the human body which is a unity ... Read More

Psalm, Psalms 100:1-2, 3, 4, 5
1 [Psalm For thanksgiving] Acclaim Yahweh, all the ... Read More

Gospel, Luke 7:11-17
11 It happened that soon afterwards he went to a town ... Read More

Saint of the Day

Saint of the Day for September 16th, 2014 Image

St. Cornelius
September 16: Cornelius whose feast day is September 16th. A Roman priest, ... Read More

Inform, Inspire & Ignite Logo

Find Catholic Online on Facebook and get updates right in your live feed.

Become a fan of Catholic Online on Facebook


Follow Catholic Online on Twitter and get News and Product updates.

Follow us on Twitter